0:00 Welcome and Introduction Presented by: Professor Ajay Shah - Executive Dean, Faculty of Life Sciences & Medicine, James Black Professor of Medicine & BHF Professor of Cardiology, King's College London SESSION 1: New strategies in dissection Moderators: Toru Suzuki, Chair of Cardiovascular Medicine/Associate Dean, University of Leicester John Pepper, Cardiac Surgeon, Royal Brompton and Harefield Hospitals 22:36 Current mortality in the setting of Type A: reflections and recommendations Presented by: Kevin Harris - Cardiologist, Minneapolis Heart Institute 37:34 How does the clinical pathway influence management of Type A? Presented by: Stephan Kurz - Consultant Anaesthetist and Intensivist, Charite' Berlin, Germany Moderator: Aung Oo, Professor of Cardiovascular Surgery, Barts Health Trust 53:42 New strategies in Type A dissection with malperfusion Presented by: Konstantinos Tsagakis - Head of Aortic Surgery, University Hospital of Essen 1:10:10 The use of PET/CT to identify serious complications in chronic dissection Presented by: Natzi Sakalihasan - Consultant Cardiovascular Surgeon, University of Liege 1:19:42 Quantitative assessment of blood flow in Type B dissection Presented by: Chloe Armour - Research Associate, Department of Chemical Engineering, Imperial College London SESSION 2: Peri-procedure decisions Moderators: Max Baghai, Consultant Cardiothoracic Surgeon, King's College Hospital, London Nick Cheshire, Professor of Vascular Surgery, Royal Brompton and Harefield Hospitals 1:38:14 The role of frailty in identifying benefit from SAVR and TAVI Presented by: Jonathan Byrne - Consultant Cardiologist, King's College Hospital 1:53:22 Industry Sponsor: Lombard Medical. New endovascular options with a single branch TEVAR device Presented by: Christoph Nienaber - Professor of Cardiology, Imperial College, London 2:06:29 Risk prediction in thoraco-abdominal and endovascular interventions Presented by: Nick Cheshire - Professor of Vascular Surgery, Royal Brompton and Harefield Hospitals 2:19:58 How to manage anti-platelet agents after coronary stenting Presented by: Simon Davies - Consultant Cardiologist, Royal Brompton Hospital 2:40:08 How to prevent embolization in TAVI and TEVAR Presented by: Richard Gibbs - Consultant Vascular Surgeon, Imperial College, London SESSION 3: The bicuspid aortic valve Moderators: Aung Oo, Professor of Cardiovascular Surgery, Barts Health Trust Ulrich Rosendahl, Consultant Cardiovascular Surgeon, Royal Brompton and Harefield Hospitals 4:03:58 Biomechanical implications of BAV aortopathy Presented by: Pouya Youssefi - Advanced Aortic Valve Repair Fellow, Pitie-Salpetriere University Hospital, Paris 4:25:10 BAV and AAD: myth or mistrust? Presented by: Thomas Schachner - Professor of Cardiac Surgery, Innsbruck, Tirol, Austria. 4:47:24 BAV: repair or replace? What is the evidence? Presented by: Pouya Youssefi - Advanced Aortic Valve Repair Fellow, Pitie-Salpetriere University Hospital, Paris 5:10:02 Are mechanical valves still an option in the era of V-in-V TAVI? Presented by: Ali Khoynezhad - Professor of Cardiovasular Surgery, Director of Aortic and Arrhythmia Surgery, MemorialCare Health System, Los Angeles, USA 5:24:20 The dilemma of Ross operation in BAV Presented by: Ismail El-Hamamsy - Professor of Cardiovascular Surgery, Mt. Sinai Hospital, New York. SESSION 4: Distal Aortic Dissection Moderator: Christoph Nienaber, Professor of Cardiology, Imperial College, London 6:09:23 Update on Acute Aortic Syndromes; what is new and how to identify? Presented by: Isidre Vilacosta - Cardiologist, Clinico San Carlos, Madrid 6:25:05 Do all aortic syndromes deserve specialist attention? Presented by: Christoph Nienaber - Professor of Cardiology, Imperial College, London 6:42:24 What is “Optimal Medical Management”? Presented by: Toru Suzuki - Chair of Cardiovascular Medicine/Associate Dean, University of Leicester 6:56:22 Should patients with known connective tissue disorders be treated differently? Presented by: Maximillian Kreibich - Consultant Cardiovascular Surgeon, University Hospital, Freiburg, Germany 7:09:53 Is heart failure triggered by TEVAR, especially in the elderly? Presented by: Maximillian Kreibich - Consultant Cardiovascular Surgeon, University Hospital, Freiburg, Germany

SESSION 5: Congenital Challenges Moderators: 0:00 Nitha Naqvi, Paediatric Cardiologist, Royal Brompton and Evelina hospitals. Conal Austin, Congenital Cardiac Surgeon, Evelina and St. Thomas’ Hospitals, London 5:07 Screening the family Presented by: Deborah Morris-Rosendahl - Consultant Clinical Scientist, Molecular Genetics and Genomic Group, NHLI, Imperial College. 28:00 Neonatal Marfan Syndrome Presented by: Nitha Naqvi - Paediatric Cardiologist, Royal Brompton and Evelina Hospitals. 44.30 Aortic dissection in teenagers. Presented by: Andreas Hoschtitzky - Consultant Congenital Cardiac Surgeon, Royal Brompton Hospital 1:04:08 The risk of aortic dissection in Pregnancy Presented by: Alex Pitcher - Confirmation pending - Cardiology Consultant, Oxford University, Radcliffe Hospital 1:26:40 The effects of turbulence: patient-specific analysis in aortic stenosis Presented by: Xiao Yun Xu - Professor of Biofluid Mechanics, Imperial College London 1:41:21 KEYNOTE LECTURE: Aortic calcification: a disease or part of ageing? Presented by: Cathy Shanahan - Professor of Cell Signalling, Kings College, London SESSION 6: Patient Interactive Workshop Moderators: Gareth Owens, Chair, Aortic Dissection Awareness, UK and Ireland. John Pepper, Cardiac Surgeon, Royal Brompton and Harefield Hospitals 2:30:56 Session Introduction Presented by: Gareth Owens - Chair, Aortic Dissection Awareness, UK and Ireland ; John Pepper - Cardiac Surgeon, Royal Brompton and Harefield hospitals 2:44:58 Surveillance and elective intervention - what works best for patients? Presented by: Bridget Lawrence - Partner of a Type A Aortic Dissection survivor 3:01:26 Post-operative follow-up - what challenges do patients experience? Presented by: Gordon McManus - Type A Aortic Dissection survivor & Head of Research, AD Awareness UK&I 3:28:07 The important role of patient carers & relatives - what do they need and want? Presented by: Susan Redward - Partner of Type A Aortic Dissection Survivor 3:46:25 Aortic Dissection in Pregnancy - how should we manage the risk? Presented by: Haleema Saadia - Type A Aortic Dissection survivor & Vice-Chair, AD Awareness UK&I SESSION 7: Getting out of trouble Moderators: Celia Theodoreli-Riga, Consultant Vascular Surgeon, Imperial College and Head of School of Surgery (HEE) Mario Petrou, Cardiac Surgeon, Royal Brompton and Harefield Hospitals 5:01:47 Valve-Sparing Aortic Root Replacement and Aortic Valve Repair - "Pearls and Pitfalls" Presented by: Pouya Youssefi - Advanced Aortic Valve Repair Fellow, Pitie-Salpetriere University Hospital, Paris 5:18:48 Cannulation strategy in acute aortic dissection Presented by: Joy Edlin - ST8 Cardiothoracic Surgery, Royal Brompton Hospital 5:27:34 Hybrid aortic repair of mycotic aneurysm - management of complex aortic disease Presented by: Urszula Simoniuk - Cardiac Surgery, NTN ACF NIHR 5:39:32 Open aortic surgery – tips and tricks Presented by: Rachel Bell - Consultant Vascular Surgeon, Freeman Hospital, Newcastle 5:51:30 My 5 top technical tips for endovascular aortic surgery Presented by: Ian Loftus - Professor in Vascular Surgery and Endovascular Surgery, St. George’s Hospital 6:04:04 Aortic trauma - a different set of challenges Presented by: Guy Martin - NIHR Clinical Lecturer in Vascular Surgery, Imperial College London & Imperial College Healthcare NHS Trust 6:18:42 Paraplegia after endovascular thoracoabdominal aortic aneurysm repair; no two cases are never the same Presented by: Jamie Kelly - ST8, St George's Hospital, London SESSION 8: Intramural haematoma and other rare presentations Moderator: Ian Loftus, Professor in Vascular Surgery and Endovascular Surgery, St. George’s Hospital 6:57:07 IMH: an early stage of aortic dissection or a different pathology? Presented by: Isidre Vilacosta - Cardiologist, Clinico San Carlos, Madrid 7:11:51 How to deal with proximal and distal IMH Presented by: Maximillian Kreibich - Consultant Cardiovascular Surgeon, University Hospital, Freiburg, Germany 7:23:26 Type A intramural haematoma: watch and wait until too late? Presented by: Will Selway - Research Fellow, Vascular Surgery, St. George's Hospital, London 7:35:22 New ideas in surveillance: graphic presentation of aortic diameter and length, mobile applications Presented by: Dominik Fleischmann - Professor of Radiology, Stanford, California, USA. CLOSING REMARKS

CHAIRS: Martin Czerny, University of Freiburg, Germany Christoph Nienaber, Royal Brompton & Harefield Hospitals, London 00:00 Contemporary issues in the treatment of complex Type B Germano Melissano, Chair of Vascular Surgery, “Vita-Salute” San Raffaele University School of Medicine, Milan, Italy 15:02 Malperfusion in Type A dissection – alternative strategies? Aung Oo, Professor of Cardiovascular Surgery and Clinical Lead for Aortovascular Surgery, Barts Heart Centre, London 36:03 Retrograde Type A – risks and ways to avoid it? Nick Cheshire, Professor of Vascular Surgery, Aortic Centre, Royal Brompton and Harefield Hospitals, London 52:40 Dissection and IMH arising in the arch – a separate entity? Tommaso Donati, Consultant Vascular Surgeon, Guy’s and St Thomas’ Hospital, London 1:10:20 Malperfusion in Type B – a stepwise approach? Colin Bicknell, Consultant Vascular Surgeon, Imperial College London 1:28:55 Should I always use a FET in arch dissection? Kamran Baig, Consultant Cardiac Surgeon, Guy’s & St Thomas’ Hospital, London

CHAIRS: Nick Cheshire, Royal Brompton and Harefield Hospitals, London Colin Bicknell, Consultant Vascular Surgeon, Imperial College London 0:00 Personal reflections on the NICE AAA guidelines from the Chair Andrew Bradbury, Professor of Vascular Surgery, University of Birmingham 18:36 The impact of Covid-19 on surgical training and the road to recovery Celia Riga, Consultant Vascular Surgeon, Imperial College London and Head of School of Surgery 35:05 Informed consent in asymptomatic patients Colm McGrath, Lecturer in Tort Law, King’s College London 54:42 Does the National Vascular Registry reflect complex surgery? Ian Loftus, Consultant Vascular Surgeon, St George’s University Hospital, London 1:07:10 Cardiovascular surgery: Quo vadis? Manoj Kuduvalli, Consultant Cardiac and Aortic Surgeon, Liverpool Heart and Chest Hospital

CHAIRS: Joseph Bavaria, Hospital of the University of Pennsylvania, USA Germano Melissano, San Raffaele University School of Medicine, Milan, Italy 0:00 Can we predict spinal cord injury after endovascular TA repair? James Kelly, Vascular Surgeon, King’s College London 10:44 An endovascular solution for Type A? Martin Czerny, Consultant Cardiovascular Surgeon, University of Freiburg, Germany 23:19 Are fluoroquinolones risky and to be avoided in the dilated aorta? Christoph Nienaber, Consultant Cardiologist, Royal Brompton & Harefield Hospitals, London 36:53 The aortic valve and the root are one organ Fabio De Robertis, Consultant Cardiac Surgeon, Royal Brompton & Harefield Hospitals, London 49:29 Rapid deployment valves: What is their role? George Asimakopoulos, Consultant Cardiac Surgeon, Royal Brompton & Harefield Hospitals, London 1:02:59 Acute aortic syndromes in London Mike Jenkins, Consultant Vascular Surgeon, Imperial College London 1:13:24 Necrotising aortitis Michael Sabetai, Consultant Cardiac Surgeon, Guy’s & St Thomas’ Hospital, London 1:24:12 Bicuspid aortic valve: When to replace the aorta Katie Francis, Honorary Clinical Research Fellow, Faculty of Medicine, National Heart & Lung Institute, Imperial College London 1:38:50 Options for reconstructing the aortic valve Cesare Quarto, Consultant Cardiac Surgeon, Royal Brompton & Harefield Hospitals, London

CHAIRS: Susanna Price, Consultant Intensivist, Royal Brompton & Harefield Hospitals Kamran Baig, Consultant Cardiac Surgeon, Guy’s & St Thomas’ Hospital, London The size of the problem 0:00 Shelley Rahman-Haley, Consultant Cardiologist, Royal Brompton & Harefield Hospitals, London 17:09 Mycotic aneurysms of the visceral segment – management? Morad Sallam, Consultant Vascular Surgeon, Guy’s and St Thomas’ Hospital, London 39:52 PET-CT for Cardiovascular Inflammation & Infection S Richard Underwood. Emeritus Professor of Cardiac Imaging, Imperial College London and Royal Brompton & Harefields Hospitals 56:28 Drug dependence and endocarditis Jullien Gaer, Consultant Cardiac Surgeon, Royal Brompton & Harefield Hospitals, London 1:11:37 Aortic graft infection: Interpreting microbiology results and maximizing treatment Nick Price, Consultant in Infectious Disease, Guy’s & St Thomas’ Hospital, London 1:31:07An algorithm for management of Prosthetic Valve Endocarditis Bernard Prendergast, Consultant Cardiologist, Guy’s & St Thomas’ Hospital, London

CHAIRS: Michael Gatzoulis, Royal Brompton Hospital and Imperial College London Katie Francis, National Heart & Lung Institute, Imperial College London 0:00 Aortopathy in pregnancy – how to advise Catherine Head, Consultant Cardiologist, Norfolk and Norwich University Hospital 17:49 Aortic dissection in pregnancy Rick Gibbs, Consultant Vascular Surgeon, Imperial College London 33:13 Aortic problems in childhood Nitha Naqvi, Consultant Paediatric Cardiologist, Royal Brompton and Harefield Hospitals, London 49:45 The hypoplastic arch – How to deal with it? Darryl Shore, Consultant Cardiac Surgeon, Royal Brompton and Harefield Hospitals, London 1:09:15 Guidelines for the management of Turner’s syndrome Michael Gatzoulis, Academic Head of the Adult Congenital Heart Centre and the National Centre for Pulmonary Hypertension, Royal Brompton Hospital and Professor of Cardiology and Congenital Heart Disease, National Heart and Lung Institute, Imperial College London

Baroness Sally Morgan of Huyton. Chair, Royal Brompton & Harefield Hospitals Clinical Group; Deputy Chair, Guy’s & St. Thomas’ NHS Foundation Trust; Master Fitzwilliam College, Cambridge